Precision Analgesia — Seed Round 2026 | Lifeline Medical Technologies

The Problem & Solution

The Problem

70-90% of drug safety alerts in EHR systems are overridden by clinicians — alert fatigue (van der Sijs et al., JAMIA 2006; Phansalkar et al., JAMIA 2013)
Doctors click past Boolean warnings — alert fatigue is endemic
MDCalc requires manual entry; low utilization at the point of care
Opioid-induced respiratory depression kills silently post-order

The Solution

SMART on FHIR CDS Hook engine — zero manual data entry
Auto-pulls patient data; surfaces a specific, guideline-cited recommendation the clinician can accept or override (override logged)
10-rule deterministic safety engine + OIRD risk scoring (PRODIGY), MME threshold logic, CDC naloxone co-prescribing prompts & pharmacogenomic guidance
<100ms response latency — specific, actionable guidance

4 Defensible Moats

①

Self-Assessed Non-Device CDSUnder the 21st Century Cures Act (FDA Jan 2026 CDS guidance), pending confirmatory review by regulatory counsel — a potential path to avoid the cost/timeline of regulated medical device software

②

Zero-PHI ArchitectureNo database. CISO-approved in weeks, not quarters

③

SMART on FHIR / Epic Lock-InNative EHR integration creates high switching costs at go-live

④

Settlement Funding WedgePoint-of-care CDS is a potentially eligible, discretionary remediation-spend category under a hospital's Exhibit E settlement allocation — subject to that hospital's own settlement administrator and state rules, not a guaranteed funding source

TAM

$6.8B*

U.S. Hospital CDS Market (illustrative estimate)

SAM

$1.4B*

Epic-Affiliated Hospitals (illustrative estimate)

ACV

$25/50/100K*

Per hospital system, by size — comp-grounded tiers (<200 / 200–500 / 500+ beds), all quotable today, plus a one-time $15–20K implementation fee

Year 3 ARR

~$2.53M*

Modeled projection — 44 hospitals at the $50K mid tier, pending Step-0 validation

Traction & Build Status

51,000+ LOC

Production codebase — TypeScript / Swift / Python

250+ ✓

iOS clinical validation scenarios passing, plus 120+ automated backend tests

iOS Beta

TestFlight deployed — physician review underway

FHIR R4

Full FHIR R4 + CDS Hooks 2.0 endpoint coverage

Epic Ready

SMART on FHIR OAuth 2.0 launch flow complete

The Ask

$2.5M

Seed · 18-Month Runway · Target Milestone: 5 Signed Hospital Contracts

30%

Engineering & Infrastructure

28%

Clinical Validation & PharmD

24%

Epic Integration & Cert.

18%

Sales, GTM & HIMSS